COVID-19: Chapter 10 - Mission Achomlished!

Seems like much ado about nothing and also more easy to correct than have a back and forth.

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It was corrected quickly. Thanks for making it worse with your back and forth!

This is true and Iā€™m sorry and sorry that Iā€™m going to make it worse. Iā€™m not mad and hope no one else is and I think this is just chatting.

Like I said before I donā€™t see churchill being abrasive here. Maybe smart-alecky.

I think this was the first abrasive post in the exchange. It was mild. Not that big a deal or anything. Should not be moderated. But, itā€™s the first post that strikes me as abrasive.

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So Iā€™ve had three shots of Pfizer, and now some natural immunity lol. There are some specific situations Iā€™ve been avoiding due to fear of getting COVID - main one being getting back to service work at the LA County Jail. Should/can I be less worried now that Iā€™ve had it, or is my risk basically the same?

Also, should this change my plans to get a fourth shot? Weā€™re traveling to Italy mid-July, so I was going to get the fourth shot mid-June. Does getting the fourth shot a few weeks after recovering from COVID make any sense?

Itā€™s a crappy decision to have to make. The more experience your system has with COVID, the better itā€™s going to handle the virus and closely-related strains. obv that doesnā€™t mean youā€™re bulletproof. OTOH, Iā€™m guessing prisons are high-risk places and the people who run them give zero fucks about their inmates getting infected. On the other other hand, I imagine the work youā€™re doing there is important.

Does that mean people who have been infected by previous variants should act as if they might have more than substantially no protection from BA.4 and BA.5 conferred by aforementioned infections.

My rheumatologist told me in March that hybrid immunity of vaccine plus breakthrough infection seems to provide very good immunity and he was holding off on recommending booster shots to anyone whoā€™s had a breakthrough infection. Talk to your own doctor but Iā€™m sure he wouldnā€™t have recommended the second booster to me if I came in with your same situation.

CDC doesnā€™t have a hard stance. Current guidelines say you can wait up to three months after initial infection because reinfection in that time period is quite rare and thereā€™s possibly a better response with waiting

Which goes against cdc, and every major organizations, recommendations!

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How long after getting pozzed do I have to wait to get a 2nd booster? Iā€™m just gonna say whatever lies I need to in order to get these every 6 months from here on out

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Youā€™d never know ā€¦ if only they had a reminder ĀÆ_(惄)_/ĀÆ

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But despite the name, thatā€™s not how ā€œimmunityā€ works, and thatā€™s not how people who study immunology talk about vaccine effectiveness.

If anyone wants to get the cliffs of this paper, itā€™s measuring antibody neutralization, not clinical outcomes. Antibody neutralization is relevant data, but itā€™s not as robust a measurement as directly measuring the percentage of people in the various populations of unvaxxed/vaxxed/boosted/boosted+prior infection/unvaxxed but infected/etc. face new infection/hospitalization/death. The lessened degree of antibody neutralization for BA.4 and BA.5 vs. BA.1, while statistically significant, was quite a bit smaller than BA.1 vs. delta and earlier strains (2-3 fold reduction vs. a 10+ fold reduction in antibody neutralization), so itā€™s very unlikely that BA.4 or BA.5 is going to be able to cause a wave as big as BA.1 did when we were still calling it omicron this past fall and winter.

Itā€™s also definitely wrong to say that there is ā€œno immunity inferred [sic]ā€ from BA.1 infection. Sera from individuals who are vaccinated and caught BA.1 showed better antibody neutralization than sera from individuals who were vaccinated but who hadnā€™t caught BA.1.

100% to this. NorCal has crazy amounts of flu right now. Testing rates, and this includes tests we send for people we think have covid, are like 13-15%. Itā€™s bad.

But he said he now understands that isnā€™t the only way the pandemic may influence infectious diseases.

ā€œWeā€™re very focused on under-vaccinated children with routine childhood immunizations because itā€™s the set-up for introduction of measles. But then there have also been a lot of kids who havenā€™t gotten the usual kind of viruses they might have been exposed to.ā€

Oh fuck me hard, we donā€™t need measles making a comeback, that is not okay at all.

You (or anyone else) think thereā€™s any chance we get rapid at home tests for flu like we have for covid? Iā€™m pessimistic, but my parents think itā€™ll happen.

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Hadnā€™t even thought about it tbh. Would make sense but I havenā€™t heard of anything about developing it.

FDA tho

Itā€™s gonna take large amounts of measles et al to change hearts and minds-if they can understand it was their own stupidity that got their kid sick. I-F.

Maybe? Probably? Iā€™ve always worked at places with rapid PCR