COVID-19 (2): Turns out it's going to be pretty bad actually

Of course I threw out the Pepcid and saved the Zantac. Dammit.

The article is worth a read:

It provides evidence that the excess mortality we’re seeing is directly coronavirus related (rather than being a feature of the lockdown) because the spike is worse in areas with worse outbreaks. This applies even within countries, like the UK has a much worse spike in London than other areas, even though everyone is under the same lockdown rules.

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Just ran to the drug store. They were out of Pepcid AC but still had some generic Famotidine, so I grabbed some. I figure if I ever start feeling sick I’ll just switch over from prilosec to this.

i’m really surprised the Nevada numbers are so low…there were confirmed cases from employees in multiple casinos way back in March. The governor is taking it very seriously, it seems, so the chances of blatant number manipulation seem to be low. Heat shouldn’t really be a factor, it turned hot this week but before that it was some of the most uncharacteristically rainy weather ever

This for sure. That totally jumped out at me as the wrong line
Also do the keeping it layman friendly thing.

Know your audience.

I was taking Pepcid like candy for a couple of years. Anything cheesy, any red sauce, anything greasy just killed. Then my doc put me on a six week course of nexium which essentially raises the pH in your stomach from blocking the acid 24/7 and lets prior stomach damage to finally heal. Since then I have an iron stomach (at least for me I don’t like spicy food).

But it does mean I have some significant leftover pepcid laying around. :grinning:

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right, that too! we were one of the earliest states with cases

I guess the most likely explanation is that it’s a relatively small metro area that got a big time signal when the casinos closed. I know those casinos like to use a lot of bleach and such so that probably helped

A couple of years ago, I figured… heh, I’ve heard folks rave about recreational oxygen, and I got this ‘alien’ stuck to my face all night long anyways… why not give it a try? So I asked the cpap folks. They said “we only do stuff by prescription, we won’t even talk to you about anything rec”. Then I asked a rec o2 place. They said “cpap is by prescription only, we won’t even talk to you about anything to do with prescriptions”. So I punted.

There exists a simple “T-value” that people who have prescriptions for medical oxygen get. Proly costs about $1 if anyone will sell it to you. Proly could use a proper non-medical substitute T-value safely. One of the reasons I punted is I didn’t feel like guessing what the safe hookup details might be. But that information is obviously out there somewhere too.

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Same for the sanitizer NY was supposedly making. Haven’t seen or heard a thing about it since Cuomo dramatic unveiling like 6 weeks ago.

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It seems likely the Zantac would have worked also. They do bind to the same receptor to stop your heartburn, but according to the link the proposed mechanism of action of the famotidine is due to binding with something else. So, I suppose it is possible that while the ranitidine is a similar molecule, it may not also bind to this other protein. In the end, probably enough doubt to justify an easy trip to the drug store.

Also, in the study, they are using intravenous famotidine at “9 times heartburn doses”. The famotidine that you take by mouth apparently doesn’t make it out of your GI tract very well. However, in the observation that inspired the study, the patients were presumably taking oral famotidine (but maybe not if they were in the hospital and on a vent). So assuming they were taking it orally (which is the most likely scenario), enough must have made it to the rest of the body to do something even when taken by mouth.

Open your eyes sheeple!

I think that was posted somewhere else and shown to be a fake. Would have fooled me, though. Still not 100% sure.

What do you mean it doesn’t work?

You shouldn’t be taking Zantac anyway, it was all just recalled because it was contaminated with NDMA.

It wasn’t observed to improve survival in hospitalized covid patients.

I’m an idiot. I should try actually reading the post he was responding to

Charlie don’t get COVID

https://twitter.com/sazzygram3/status/1253787079626100736?s=09

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I was late to the pulse ox game and it cost me time and money. Still way ahead of the general population though.

I ordered the Oxymeter on March 9

Ordered on March 9, 2020 (2 items)

[Pulse Oximeter Fingertip, ATMOKO Pulse Oximeter Finger Oximetry SPO2 Blood Oxygen Saturation Monitor Heart Rate Monitor Rotatable OLED Digital Display]

ATMOKO