Gotta love some of the comments. “But what about side effects, what if it hurts your heart?”
Bitch, Im 300 pounds. Nothing can hurt my heart more than the status quo
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Researchers in Denmark
Aren’t the Danes a healthy population compared to your average country? Are they just tired of working out to keep up with it or something? I support their efforts, it just surprises me the research isn’t originating from a country with a less healthy population.
Doesn’t sound like it gives the actual benefits of running a 10k as in increased lung function, etc but just mimics the metabolic effect after running a 10k. Maybe beneficial but the same as a 10k seems like overselling it.
Last week, the US Food and Drug Administration announced that tirzepatide is no longer in shortage. It has been a long time coming: The active ingredient in the weight-loss drug Zepbound and diabetes medication Mounjaro has experienced runaway popularity, along with other GLP-1 meds like Ozempic. This unprecedented demand sent it into shortage in December 2022. The end of drug shortages are usually a good thing—but for many people currently taking tirzepatide, this is a moment of fear and uncertainty rather than celebration. For them, this means the meds they are accustomed to taking may be harder to get.
There are two types of pharmacies permitted to compound drugs, known as 503a and 503b pharmacies. With the shortage ended, 503a pharmacies need to cease nearly all production of copies immediately; 503b pharmacies, which typically make larger quantities, have a 60-day off-ramp period. Most of the pharmacies compounding these meds are 503a—which means that the supply is already slowing, and in some cases lurching to an abrupt halt, for a large number of people who have come to rely on this medication. “It would make sense that people would panic over a shortage,” says Maria Rising, a compounded tirzepatide patient who also runs a popular Instagram channel about the medication. “But they’re actually panicking because the shortage is over.”
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yeah I’m guessing there’s going to be a very profitable foreign market
Exercise affects so many systems that I’ve read pretty convincing arguments that an exercise pill is impossible in principle. There’s just a ton of stuff that happens during exercise. Altering a few measurable biomarkers (in rats) is not akin to widespread systemic changes.
Is it amphetamines mixed with cocaine?
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Oh ok so it’s only as good as running a 5K. Suppose that’ll do.
Just take two?
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Fat Joe isn’t even fat anymore because of woke.
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Good thing his secondary nickname is Joey Crack.
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I went the Hims route and ordered the shots. I took the first shot last week. One week of progress means SW:288 and CW: 286. No major side effects. Hunger is there but getting full faster.
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https://x.com/yashar/status/1847016036509667538?t=SHtp7RDp-TgFbU6ZKU--rw&s=19
RIP another bbw lost to drugs
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I’m going through a very similar story. These drugs really are magical. My issue with weight loss has never been hunger per se, but rather craving yummy foods and whipping a bowl of ramen noodles or something at 10 at night. Even with the intro dose of semaglutide, I’m finding that craving element is gone. I still enjoy good food, but I find it a lot easier to just eat when I’m hungry and stop eating when I’m full.
What I find interesting is that before I went to Hims, I talked to my PCP. He’d previously been on me about losing some weight, and he seemed particularly concerned that my blood pressure was borderline. When I asked him about GLP1s at my last visit, he was like “Eh, your BMI is only 32 and your BP is 121/82, these drugs are for people with a much more serious weight problem.” I had the disturbing sense that when the solution for overweight patients was to scold them to be more active and eat less, these warning signs were a lot more salient than when the solution is a prescription. I somewhat understand, but I’m pretty sure that <10% of patients who would seriously benefit from these drugs are actually getting them currently. Huge public health fail.
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Fatties are still acceptable targets for shame and ridicule. Being fat is seen as being lazy and a moral failing instead of a medical condition that can be treated. I’m sure it will get better under the caring supervision of Trump…
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Yeah my PC is still hesitant even though Im rocking a 41 BMI.
But he did suggest a great diet to me, even thought Ive plateuaed for 4 months now.
So, thats fun.
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What’s holding you back from getting an online prescription? The online pharmacy route was MUCH less sketchy than I was expecting, and it’s not even like this is some experimental, off-label treatment. These drugs are approved for weight loss, and there’s no real doubt that being at a 41 BMI is terrible for your health long-term.
For me, I eventually realized that:
- I didn’t have much doubt that I’d be significantly healthier taking the drugs, and
- I could get them legally, safely and a sort-of reasonable cost.
If those things are both true, what’s the argument?
money
I think insurance will pay at a BMI that high.