Besides them, I’ve encountered people my age and younger with hypothyroidism. Haven’t heard that mentioned as an issue. But they were all women, so even if it was an issue, it wouldn’t come up if I was around. But I can think of two who had it, got married, had kids and continue to be ostensibly happily married. So chances are it probably had little effect.
Can’t think of any younger guys that I know who have it. But intuitively doesn’t seem like it would be a problem. As long as you are getting the right amount of thyroid hormone, I’m not sure if your body cares that much whether you are ingesting it in pill form or making it yourself. So I’d be optimistic that sexual function would be unaffected for most hypothyroid men who are appropriately treated.
This is correct, no big deal at all. My thyroid got whacked by radiation so I take a Levothyroxine pill every morning and don’t even think about it. It’s consistently one of the most prescribed medications in the US.
Immunology was a loooong time ago. Basically HLA is the part of the immune system that displays a broken down virus on the surface of the infected cell that attracts killer T-cells to destroy the infected cells (it also identifies transplants as others-leading to rejection and plays a role in some autoimmune disorders).
So people with certain HLA variants don’t function as well others. These variants are based on ancestral origin.
This is not a terribly impressive study. The first two parts of the study are statistical analyses of bulk data, and the first part doesn’t even support the second part. The third part is entirely in silico, without any in vitro, in situ, or in vivo experiments to back up the computational predictions. To me, the conclusions of this paper read more like hypotheses to be tested by the experiments that will actually mean something.
