@joltinjake already posted this, but I wanted to extract some of the money quotes, which in fact do not serve to make me any less paranoid. (But it seems to be a very well sourced and fair article, which imo supports the views of the “conspiracy theorists” ITT.)
One of the few scientists to speculate publicly was the well-known Rutgers microbiologist Richard Ebright. “The possibility that SARS-CoV-2 entered humans as a direct result of the activities of PREDICT—during field collection of bats and bat excreta, or during laboratory characterization of bats, bat excreta, or bat viruses—cannot be excluded and cannot be dismissed,” he told me, comparing the idea of actively seeking new viruses in remote places and bringing them back to labs (in densely populated areas) to “looking for a gas leak with a lighted match.”
“It’s important to be upfront that we do not have sufficient evidence to exclude entirely the possibility that it escaped from a research lab,” the respected University of Washington biologist Carl Bergstrom wrote on Twitter. Though he called a natural zoonotic spillover “far more plausible,” he cautioned: “Whatever the origin of #SARSCoV2 may have been, going forward we need to carefully assess and manage the risk associated with a range of activities.”
There’s already been one lab-caused mini-pandemic, in 1977, when a strain of influenza erupted in China and swept the globe. (Luckily, it was a mild one.) Flu strains are famous for constantly mutating, but this one was nearly identical to one last seen in the 1950s, meaning it had been held somewhere in suspended animation. Suspicion fell on the Soviet Union’s robust bioweapons program, but researchers concluded the pathogen had more likely been released during a vaccine trial gone wrong. Nobody fessed up.
The original SARS has not reemerged from the wild since 2003, but it has actually escaped from three different labs, one in Taiwan, one in Singapore, and one at China’s National Institute of Virology in Beijing, where two researchers were infected. The researchers mistakenly believed they were handling a version of the virus that had been inactivated.
The biosecurity expert Lynn Klotz, together with science journalist Edward J. Sylvester, surveyed the CDC’s lab accident data and conservatively estimated the chance of a pandemic pathogen escaping a lab at just 0.3 percent per year, meaning there would be an 80 percent chance of an escape from a single lab over 536 years of work. Perhaps that would be acceptable, but they quickly counted 42 labs known to be working with live SARS, influenza, or smallpox, which translated to an 80 percent chance of an escape every 12.8 years. And that was in 2012, when such work was far less commonplace than it is now. The two later estimated the likelihood of an escaped virus seeding “the very pandemic the researchers claim they are trying to prevent…as high as 27%, a risk too dangerous to live with.”
In 2010, 244 unintended releases of bioweapon candidate ‘select agents’ were reported. Looking at the problem pragmatically, the question is not if such escapes will result in a major civilian outbreak, but rather what the pathogen will be and how such an escape may be contained, if indeed it can be contained at all.”