Covid being the Pandora virus is some great last act writing. Sets up the sequel perfectly.
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If you read that whole study on t-cell exhaustion you deserve some sort of prize. I didnāt either, but Iām pretty sure youāre interpreting it wrong. It sounds like in the context of that study the āexhaustedā cells were preferable since they caused less inflammation and subsequent damage. Iām not 100% sure of this either because it was dense AF.
The other study was limited to individuals with long COVID (more than 12 wks). If those were the people getting monkeypox, I think weād have heard of it.
Those are the first two studies I found, there are plenty more out there and people who seem to be knowledgeable on Twitter are speculating that this is a distinct possibility. I could very well be interpreting that study wrong, but either way we know COVID can impact T-cell functionality for some period of time, we know that COVID is ripping around the world right now, and weāre seeing a monkeypox outbreak.
I think itās too early to know stuff like that.
T-cell stuff is super speculative imo. Claiming this as a result of it isnāt really supported yet.
100%, but also not dismissible yet. Long-term consequences to the immunes system are one of the risks (and not the worst one) of our mass infection strategy.
To be clear, Iām not claiming it is, Iām saying itās one of the most likely possibilities. To me thatās more likely than a surprise mutation of monkeypox virus with nobody finding out until it spread the world. Although thatās very possible, too.
The most likely possibility, by far, is just bad luck
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Bad luck as in the R0 is still < 1 and itās just getting lucky and managing to spread through super spreader events?
Bad luck as in shit happens and new diseases emerge all the time. It doesnāt have to be covid related.
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There are outbreaks like yhat all the time, I wouldnāt read too much into it yet.
Donāt think we really even know if thereās significant community monkeypox spread yet.
Some hyperawareness is natural. As a society we could sure as fuck prepare and try not to be so stupid next time, but we probably wonāt.
Sure, but this isnāt a new disease. Itās possible it mutated, but so far nobody has any evidence of that. It seems that a mutation or a weakening of immune systems would be two leading possibilities, and only an epidemiologist could handicap those odds and even then youād probably see a ton of variance.
I mean itās in the UK, Spain, Portugal, Sweden, Canada, and the US now. Thatās an awful lot of spread to have it be not spreading human-to-human. I hope itās not, but Iām not optimistic at the moment.
Hard disagree on that. Iāve got an epidemiologist in the family and weāve had lots of convos since COVID began. They are great with things like stats and study design but their understanding of disease pathophysiology is pretty limited. Unless they are both epidemiologists and MDs. Those would be the folks that you want speculating. Or a group that included some of each.
Thatās a good point since one side of it is epidemiology and the other side is more medical.
https://twitter.com/fitterhappieraj/status/1527200411416940544?s=21&t=6kFhDS3-IRCFujauPpUNvg
https://twitter.com/fitterhappierAJ/status/1527200420736688128
https://twitter.com/fitterhappierAJ/status/1527200428835885057
https://twitter.com/fitterhappierAJ/status/1527200430442397697
Not necessarily, these kinds of things do flare up. There was a monkeypox outbreak in ā03 that hit 71 people all across the Midwest. This is more widespread than that, though.
Thank you, Texas Guy, for importing rats into the US, we were having a real shortage of those here.
Yeah, but that was all animal to human and confined in a region where the prairie dogs had been imported. This is far more widespread, making it a lot less likely to be animal-to-human transmission.
We should check to see if these people were all involved in some international rat import/export business. Which is a thing for some reason.